TY  - JOUR
AU  - González, Alejandro H.
AU  - Rivadeneira, Pablo S.
AU  - Ferramosca, Antonio
AU  - Magdelaine, Nicolas
AU  - Moog, Claude H.
TI  - Stable impulsive zone model predictive control for type 1 diabetic patients based on a long-term model
JO  - Optimal Control Applications and Methods
JA  - Optim Control Appl Meth
VL  - 41
IS  - 6
SN  - 0143-2087
UR  - https://doi.org/10.1002/oca.2647
DO  - https://doi.org/10.1002/oca.2647
SP  - 2115
EP  - 2136
KW  - impulsive control systems
KW  - type I diabetes model
KW  - zone model predictive control
PY  - 2020
AB  - Summary In this work, the problem of regulating blood glucose (glycemia) in type I diabetic patients is studied by means of an impulsive zone model predictive control (iZMPC), which bases its predictions on a novel long-term glucose-insulin model. Taking advantage of the impulsive version of the model?which features real-life properties of diabetes patients that some other popular models do not?the given control guarantees the stability under moderate-to-severe plant-model mismatch and disturbances. Long-term scenarios?including meals and physiological parameter variations?are simulated and the results are satisfactory as every hyperglycemic and hypoglycemic episodes are suitably controlled.
ER  -