2019-10-282019-10-282018Guntero, Vanina A.; Mancini, Pedro M.; Ferretti, Cristian A. ; Kneeteman, María N. Synthesis and encapsulation of bis-eugenol in a mesoporous solid material: enhancement of the antioxidant activity of a natural compound from Clove Oil. Sciencedomain. 2018http://hdl.handle.net/20.500.12272/4109In the present work, microwave extraction conditions to recover high eugenol content in the crude extract from clove were investigated. The effect of factors like temperature, stirring, time, liquid: Solid ratio and solutions of solvent were evaluated with Taguchi’s method. The eugenol content was determined by gas chromatography. From the isolated eugenol, the bis-phenol was synthesized by the dimerization of eugenol. The encapsulation of bis-eugenol on the mesoporous silica was carried out by a microwave assisted process. Previously, mesoporous silica SBA-15 was prepared by hydrothermal synthesis using Pluronic P123 triblock copolymer as a surfactant. The bis-eugenol encapsulated in SBA-15 was characterized by physicochemical techniques. The results indicated that the encapsulation of bis-eugenol in the pores of silica occurred through weak interactions of an electrostatic nature without producing chemical changes in the antioxidant property. The antioxidative activity of eugenol, bis-eugenol and bis-eugenol/SBA-15 system was examined by phosphomolybdenum assay. Among these materials, a remarkably high antioxidant activity was found in bis-eugenol encapsulated in SBA-15. These resultas suggest the possibility of applying this system as an antioxidant active packaging in the future.application/pdfenginfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/antioxidant activityencapsulationmesoporous materialclove oilinfo:eu-repo/semantics/articleAtribución-NoComercial-CompartirIgual 4.0 Internacional