Facultad Regional San Francisco

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    Enhancement of extraction parameters for bioactive substances from ocimum basilicum leaves through sonotrode-assisted ultrasonic extraction
    (RICIFA, 2023-11-16) Aloisio, Carolina; Razola-Diaz, María del Carmen; Aznar-Ramos, María José; Longhi, Marcela; Andreatta, Alfonsina E.; Verardo, Vito
    Sweet basil (Ocimum basilicum) leaves are rich in bioactive compounds that present therapeutical benefits for human health. Ultrasonic-assisted extraction (UAE) is frequently used to obtain phenolic compounds in plants. However, few works have developed multivariable studies to find the optimal conditions to extract the maximum amount of compounds, especially applied to UAE via sonotrode. The purpose of this work was to perform a multi-variable study employing a Box–Behnken design to collect the highest active compound content from Ocimum basilicum leaves. The efficacy of the design was endorsed by ANOVA. The studied parameters for UAE via sonotrode were ethanol/water ratio, amplitude and time. The analyzed responses were the rosmarinic acid, sum of phenolic acids and sum of phenolic compounds content. Optimal conditions were found to be 50% ethanol/water, 50% amplitude and 5 min. 27 bioactive compounds were identified by HPLC-ESI-TOF-MS, when the extract was collected by applying the optimal conditions. Ocimum basilicum may be appreciated as a valuable source of important bioactive substances for pharmaceutical use.
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    Recovery and purification of intermediate products of dicarboxylic acid esterification.
    (Universidad de Valladolid, 2023-03-21) Sánchez, Francisco A.; Andreatta, Alfonsina E.; Pereda, Selva
    Recovery and purification of intermediate products of dicarboxylic acid esterification.
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    GCA-EOS modeling of mono- and di-carboxylic acids for phase equilibria prediction by group contribution
    (Universidad de Tarragona, 2023-06-21) Sánchez, Francisco A.; Andreatta, Alfonsina E.; Pereda, Selva
    Carboxylic acids are present in a wide range of industrial processes, including the production of nylon, biodegradable plastics, soaps and detergents, and pharmaceuticals. Low molecular weight carboxylic acids appear frequently in a number of industrially important waste streams, from which they must be recovered, preventing pollution and generating a profit. On the other hand, high molecular weight carboxylic acids (i.e. fatty acids) derived from fats and oils, are used in the production of coverings, surfactants, plastics, and cleaning products. Dicarboxylic acids are also industrially important compounds.